THE EFFECTIVENESS OF POSTOPERATIVE REHABILITATION METHODS IN PATIENTS WITH PURULENT-NECROTIC COMPLICATIONS IN THE MAXILLOFACIAL REGION ASSOCIATED WITH SYSTEMIC VASCULITIS
Keywords:
Systemic vasculitis, maxillofacial region, purulent-necrotic complications, surgery, rehabilitation, wound healing, functional recovery.Abstract
Purulent-necrotic complications that arise in the maxillofacial region against the background of systemic vasculitis are characterized by a severe clinical course, tissue ischemia and destruction, prolonged inflammation, infectious risk associated with immunosuppressive therapy, and delayed wound healing. Therefore, postoperative rehabilitation in such patients is of particular clinical importance. According to current literature, ANCA-associated vasculitis is a rare but life-threatening disease. Changes in the oral cavity and maxillofacial region, particularly in granulomatosis with polyangiitis, can sometimes be one of the earliest signs of the disease. Furthermore, the risk of local infection and delayed healing increases following invasive dental and maxillofacial procedures in the context of immunosuppression.
References
1.Alamoudi WA, Sollecito TP, Stoopler ET, France K. Oral manifestations of anti-neutrophil cytoplasmic antibody-associated vasculitis: an update and narrative review of the literature. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2023. doi:10.1016/j.oooo.2022.11.013.
2.Capodiferro S, Limongelli L, Favia G. Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview. Medicina (Kaunas) . 2021;57 (3):271. doi:10.3390/medicina57030271.
3.Chuhuaicura P, Rodríguez-Niklitschek C, Oporto GH, Salazar LA. Distinct Molecular Mechanisms in Oral Mucosal Wound Healing: Translational Insights and Future Directions. International Journal of Molecular Sciences. 2025;26 (21):10660. doi:10.3390/ijms262110660.
4.Chung SA, Langford CA, Maz M, et al. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis & Rheumatology. 2021;73 (8):1366-1383. doi:10.1002/art.41773.
5.Day J, Crawshaw H, Lim KW, Pauling JD, Gunawardena H. An Update on Vasculitis for the General Physician. British Journal of Hospital Medicine. 2025;86 (3):1-21. doi:10.12968/hmed.2024.0435.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Ideal Journal of Multidisciplinary Research

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.






