FEATURES OF COMPLEX THERAPY OF CHRONIC TUBULOINTERSTITIAL NEPHRITIS IN CHILDREN
Keywords:
Chronic tubulointerstitial nephritis, rutin, electrophoresis.Abstract
Chronic tubulointerstitial nephritis (CTIN) is one of the most pressing problems in modern pediatrics. The aim of this study was to develop a method for the comprehensive correction of CTIN in children taking into account the identified pathogenetic significance of protein metabolism parameters. Material and methods. The patients were divided into 2 groups: Group 1 consisted of 41 patients who received the drug "Rutin" along with traditional therapy, group 2 consisted of 37 patients who received complex therapy: the drug "Rutin" + electrophoresis with 0.5% euphyllin, aged 4 to 15 years. Results. As a result of studying the effectiveness of complex treatment based on protein metabolism parameters, a reliable decrease in kidney damage molecules (KDM) in the urine was determined, regardless of the initial level of endogenous intoxication (EI) and the form of the disease. Discussion. Complex treatment turned out to be significantly effective for all analyzed clinical symptoms of the disease compared to other groups of patients with CTIN. Conclusion. The treatment method we offer is the most effective way to treat CTIN.
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